Pactimibe: New Drug Found Promoting Disease
CategoriesCleveland, OH (AHN) - Research spearheaded by Steven E. Nissen, M.D., Medical Director of the Cardiovascular Coordinating Center at The Cleveland Clinic, has discovered that a new generation of drugs, intended to inhibit the buildup of plaque in arteries, is ineffective.
Pactimibe, the first ACAT inhibitor or plaque-deterring drug to reach phase III trials, was found not only to be ineffective in reducing the progression of coronary artery disease, but also in some cases to even promote it.
Researchers had hoped this drug would signal a new era in treating coronary artery disease since the introduction of statins, a class of drugs that blocks the production of cholesterol in the liver.
"While the results are disappointing, we did come away with several important conclusions," Dr. Nissen said. "A number of drugs in this class are under development and while they are promising, in this study Pactimibe didn't work. It is better to know now that researchers need to reexamine the safety profile of this class of drugs and perhaps even redirect their strategies."Coronary artery disease remains the leading cause of death in the United States. Since the introduction of statins in 1987, there have not been significant advances in drug treatments for the disease.
(end of article. source: allheadlines.com)
My comment:
This is just another drug that turns out "not really up to snuff".
But why do we need a host of new drugs at all? If heart disease is nutrition-related, as seems to be the case, why can we not just supply the proper nutrients for our bodies to do their oown routine repair work?
You guessed it: There's no profit in it for pharma. That is why we will have drug after drug - one less effective than the other - because we are working stuck in a drug paradigm. Give the body the nutrients it needs and it will be well. Fill it full of drugs and it will be full of problems.
Too simple?
posted by Sepp Hasslberger on Wednesday November 16 2005
URL of this article:
http://www.newmediaexplorer.org/sepp/2005/11/16/pactimibe_new_drug_found_promoting_disease.htm
