Share The Wealth by Chris Gupta
May 19, 2004

Comprehensive Nutrient Review

..."as nutritional supplements are derived from nature and cannot be patented, the pharmaceutical industry has viewed them as a competitive threat to their patented drugs. Motivated by significant financial incentives, the pharmaceutical industry has sought to suppress the use of supplements, which cannot be patented, and limit their potencies. Much of their efforts have been focused on lobbying for legislation to limit the public's right to take supplements at higher dosages, or in sponsoring studies to show that supplements are not effective for therapeutic purposes."...

This much needed article should, once and for all ("particularly at therapeutic dosages"), put an end to the deliberate confusion promulgated by the vested interests on the efficacy of nutrients.

To add insult to injury much doubt has been created on the safety of these nutrients which in many cases are far safer than everyday foods we consume.

"It's fascinating how when there is one suspected adverse reaction to a dietary supplement it makes the headlines, and yet officials and the media are oblivious to the plethora of deaths due to properly regulated, properly prescribed and properly used drugs not to mention avoidable deaths due to medical misadventure. This graph highlights the relative safety of dietary supplements compared to many other causes of death. (US Data). - Ron Law

Typically, over regulation is used as a tool to curb competition in the name of efficacy and safety frequently at the expense of generally safe, efficacious and cost effective non patentable alternatives and/or non MD practitioners.

Chris Gupta

See also: Roots of Medical & Other Monopolies

COMPREHENSIVE NUTRIENT REVIEW Gary Null PhD, Carolyn Dean MD ND, Robert Dean, Christine Wheeler MA, James Yeargin

Note: The information on this website is presented for educational purposes and is not a substitute for the advice of and treatment by a qualified professional.

When it comes to nutritional supplements, the public is confused and does not know what to believe. A current but long standing controversy over the effectiveness of nutritional supplements for purposes of preventing and treating disease has involved two distinct factions. On one side are those in mainstream medicine who view nutritional supplements as non-therapeutic, but necessary for the prevention of classically defined illnesses such as beriberi, pellagra, and scurvy. This more traditionalist group believes that supplements should be consumed only in small quantities such as those stated by the U.S. Food and Drug Administration (FDA) in their published Recommended Daily Allowances (RDA). This same group tends to dismiss that supplements taken at higher than RDA doses can have any measurable impact upon human health. To date, this traditionalist group has been the predominant force in directing national policy on the use of nutritional supplements. Another smaller, yet growing group believes that taking a variety of nutrients in doses substantially higher than the RDA, does have an impact on human health in ways that are not only preventative, but also therapeutic. This "alternative health” group believes that supplements taken in larger than RDA quantities can both prevent disease and treat it. This latter group has had little or no influence on national policy or standards.

Meanwhile, the public has been increasing its consumption of vitamins and nutritional supplements, believing that this is good for their health. Such increased consumption has occurred despite the efforts of pharmaceutical companies and orthodox medicine to advise the public that taking increased doses of supplements above RDA levels has no effect on either preventing or treating disease. However, as nutritional supplements are derived from nature and cannot be patented, the pharmaceutical industry has viewed them as a competitive threat to their patented drugs. Motivated by significant financial incentives, the pharmaceutical industry has sought to suppress the use of supplements, which cannot be patented, and limit their potencies. Much of their efforts have been focused on lobbying for legislation to limit the public's right to take supplements at higher dosages, or in sponsoring studies to show that supplements are not effective for therapeutic purposes. Recently, the World Trade Organization (WTO) has also threatened to limit the availability of supplements through "harmonization” procedures that accept only the most rigid standards set by those countries with the most restricted access to supplements. Congress has also recently sought to schedule hearings to determine whether the availability of supplements in certain dosages should be further regulated in the United States.

The debate over supplements, including their efficacy at various dosages and their ability to either prevent or treat disease, has therefore become an important topic in public health today. In this comprehensive review, we sought to assemble the most relevant scientific evidence on the efficacy of nutritional supplementation, and to resolve one of the most enduring and vexing issues in public health policy, whether consumption of supplements at levels higher than the RDA has either a preventative or therapeutic benefit on human health.


We performed a comprehensive review of scientific studies on the efficacy of 50 selected nutrients in preventing, retarding, and treating disease. These studies were culled from a much larger online database of 484,000 studies contained in peer reviewed health, nutritional, and scientific journals. Based on this research, we conclude that there is a significant body of evidence demonstrating that the 50 selected nutrients are effective at preventing, retarding and even improving disease. The studies, as a whole, show that the nutrients are effective at both preventative and higher therapeutic dosage levels. Further, these studies demonstrate that the effective therapeutic dosages are significantly higher than had been generally argued by even alternative health groups.

We believe that this is the first time there has been a scholarly effort to assemble and summarize such a massive number of peer reviewed studies on such a wide assortment of nutritional supplements. Previously arguments made by both traditionalist and alternative health groups have relied on specific studies, or at most, a group of studies on a single nutrient. Many of these studies were sponsored by parties with a vested interest in the conclusion. Such data, we suggest, was insufficient to make broad pronouncements on the efficacy of supplements as a whole. Here, however, we have utilized a significantly larger number of studies covering a much broader range of nutrients. Accordingly, we can have much greater assurance that we have reached correct conclusions about the efficacy of nutrients as a whole, particularly at therapeutic dosages.

We hope that this collected studies of nutrients, and the summaries presented, will bring new national attention to the existence of nutrients and the important role that they can play in maintaining and optimizing human health. We suggest that the nation's leading medical authorities examine the results demonstrated by this comprehensive review so that they can begin to adopt and implement nutritional protocols at therapeutic dosages for purposes of preventing and treating disease.

Click Here for the Codex Nutrient Chart

Summary of the research on each nutrient is included in the orignal article


posted by Chris Gupta on Wednesday May 19 2004
updated on Monday March 13 2006

URL of this article:



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Readers' Comments

Thanks for sourcing this valuable information. It should be given to every practising physician in Canada.

Posted by: on May 21, 2004 12:50 PM


I have taken myself off 20mg of lipitor due to crippling muscle and joint pain. what would be the replacement dose of red rice yeast and coq10 be? I also take celebrex, cozar and nexium. I really want to get off the drugs.

Posted by: karin on May 20, 2006 12:27 AM


Hi, can you get on coast to coast with Art Bell again, this time to talk about the threat to supplements. Tens of millions will hear it.


Posted by: Gladys Luna on December 23, 2006 10:34 PM


I am trying to find the comprehensive nutrient review by Gary Null et al. Anyone have any idea where to find? Pls e-mail me directly. Thanks

Posted by: Jeff Maynard on March 31, 2007 03:19 PM


Comprehensive Nutrient Review did not stay easily available very long. Seems to be intact as an Archive. Take me back: CODEX Alimentarius. Canada's Police State Bill C51 Camouflaged As A Health Bill by Daniel J Towsey On April 8th 2008 The Health Minister of Canada introduced a totally unnecessary bill, that is quickly being forced through Parliament to attack the Natural health products and services industry on behalf of big Pharma. The public is being deceived and not informed of the police state provisions written into this bill. The government is using the slogan that we need this new bill to protect our health. That's a complete fraud and deception. We already have all the necessary laws in place to protect us. Unlike the regulated prescription drugs, no one has ever died from consuming or using any alternative natural health therapies, products or services. And believe me, if anyone had. The law would have quickly stepped in with our previously existing and very effective laws . Under Bill C-51 the State could: · Enter private property without a warrant · Take your property at their discretion · Dispose of your property at will · Not reimburse you for your losses · Seize your bank accounts without a warrant · Charge owners shipping and storage charges for seized property · Store your property indefinitely · Levy fines of up to $5,000,000.00 and/or seek 2 years in jail per charge · Will not have to report seizures to a court. · They can charge you just for talking about or promoting natural alternatives With your assets and money under their control will you be able to defend yourself in Court? CANADA stop bill C51! Toronto Rally May10-2008 Chris Gupta Bill C51 Spred the Meme

Posted by: Dan Burdick on June 10, 2008 06:28 PM


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Be sure to consult your health practitioner of choice prior to any specific use of any of the non drug device or food based medicinal products referenced herein.



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