Cholesterol Does Not Cause Coronary Heart Disease
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Cholesterol Does Not Cause Coronary Heart Disease, Statins Don´t Work by Lowering Lipids. The Role of Inflammation and Stress.
Paul Rosch; MD, FACP, Clinical Professor of Medicine and Psychiatry, New York Medical College, President, The American Institute of Stress, Honorary Vice President, International Stress Management Association, 124 Park Ave.Yonkers, NY 10703, USA.
1. Increased dietary fat intake does not significantly elevate cholesterol or lipid levels.
2. Elevated serum cholesterol and/or other lipids are not the cause of coronary heart disease.
3. Statins can have significant side effects that have been overlooked or deliberately suppressed. In addition to rhabdomyolysis and liver dysfunction, these include: muscle pain, weakness and fatigue and biopsy evidence of myopathy and tendinopathy in the absence of elevated CK, memory loss, global amnesia, difficulty in sleeping and concentration, erectile dysfunction, problems with temperature regulation, difficulty in managing diabetes, and peripheral neuropathy.
4. All statins have been shown to be carcinogenic in experimental animals in dosages that approximate those given to patients. Although the lag time between exposure to a carcinogen and clinical detection is often a decade or more, a disturbing increase in breast cancer has already been reported in the CARE trial as well as certain skin malignancies in the simvastatin trials. Statins could initiate and/or accelerate malignant growth by a) blocking the production of Coenzyme Q10, which has been shown to have anti-cancer effects; b) stimulating the growth of new blood vessels that malignancies require to promote their propagation; c) decreasing the cytotoxicity of natural killer cells; d) blocking the production of squalene, an intermediate cholesterol metabolite with anti-cancer activities in animal studies and currently used as adjunctive therapy in treating cancer; e) reducing the production of DHEA, which has been shown to have anticancer and immune stimulating effects in experimental studies.
5. Cardioprotective effects are seen regardless of baseline cholesterol or LDL levels or the degree to which they are reduced and are achieved far too rapidly to be due to lowering LDL. If statins worked by lowering LDL one would expect to see dose-response relationship, which has not been demonstrated in any statin trials. Cardioprotective effects are seen in the elderly where LDL or other lipids are not a risk factor for coronary heart disease and in the HPS study statin treatment also prevented ischemic stroke although high LDL is not a risk factor for stroke.
6. There is abundant evidence that reducing inflammation, thrombotic factors and endothelial
damage may explain the statin effects. For example, in the CARE, the outcome was related to the degree of inflammation but independent of any lipid response.
7. Most coronary events are not due to progressive blockage of a vessel by gradual accumulation of lipid material but to thrombosis and disruption of an asymptomatic fibrous plaque with minimal protrusion. Human atherosclerotic plaque bears little resemblance to experimental atherosclerosis in animals force-fed high-fat and high cholesterol diets, but has all the hallmarks of an inflammatory response to infection and there is considerable evidence to support such an etiology, particularly for chlamydia pneumoniae. Homocysteine, angiotensin II and a host of inflammatory agents have also been implicated.
8. Therefore, the current therapy goals of lowering LDL to arbitrary levels are not only inappropriate but also dangerous, since this will only lead to larger doses and more side effects.
Stress can contribute to the pathogenesis of coronary heart disease via a number of well documented neuroendocrine activities. With respect to inflammation, it should also be noted that CRP levels correlate best with abdominal obesity, which has been shown to be largely due to increased cortisol activities that increase adipocyte production of inflammatory cytokines. In addition to these chemical/molecular pathways there is an emerging paradigm of communication at a physical/atomic level that may help to explain other stress-related cardiovascular effects as well as the success of novel "energy treatment" effects.
http://www.thincs.org/WAPF2003.htm#Uffe
posted by Chris Gupta on Thursday January 29 2004
updated on Saturday September 24 2005
URL of this article:
http://www.newmediaexplorer.org/chris/2004/01/29/cholesterol_does_not_cause_coronary_heart_disease.htm
Readers' Comments
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: David on March 3, 2004 05:11 PM
Thanks for the link to this page
Posted by: Allison on April 13, 2004 02:09 PM
looks like statins are DANGEROUS!
I have yesterday been prescribed 10mg of atorvastatin calcium...after viewing postings on this site I now will be looking INTENSIVELY for alternatives. THANKS!
Posted by: isobel on May 25, 2004 03:32 AM
For information go to: http://www.health-heart.org/
Posted by: Chris Gupta on May 25, 2004 08:12 PM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Mike on May 31, 2004 06:35 PM
Mike, I suspect just using the CQ10 along with the C & B vitamins, alone might be all all that you need. See:
Orthomolecular Solutions to Heart Disease
Posted by: Chris Gupta on May 31, 2004 08:14 PM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Mike on May 31, 2004 08:18 PM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Nancy on June 27, 2004 04:42 AM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: ZiZi Ann Scott on July 20, 2004 02:58 AM
I have contended with "Tin Woman" syndrome for a very long time now. I thought that it was 100% due to osteoarthritis resulting from injuries sustained in an auto accident as well as fibromyalgia. Every muscle in my extremities and even my feet hurt.
Most recently I underwent surgery was off of statins for more than two weeks. During that time the only pain I had pertained to the surgical site.
I went back on the statins a couple of days ago and have been feeling like the rust tin woman again..OUCH.My energy is zapped as it hurts so much to move. I never for a moment connected the two things: statin, muscle aches.
I just happened upon this site bc I was looking up "CK levels" as I had beeb reviewing a pre-surgical blood screen and noted that mine was 294, putting in the high range.
I am going to try an experiment and go off of the statins for a few days again. In the meantime I will take Co Q and B6 and 12 and Folate. I wonder if Red Yeast Rice, known to lower cholesterol, has the same negative effects as statins do. Any one know this?
Posted by: Patricia on August 5, 2004 03:55 PM
i actually cannot beleive that this site is online! statins are a major 1st line drug that lowers cholesterol (a well known proven medical fact).
but besides that i suggest that instead of taking drugs to lower cholesterol u all consider healthy eating, a healthy lifestyle and exercise!
Posted by: Hayley on August 17, 2004 03:06 PM
Hayley,
Reducing cholesterol is not a good idea to begin with - there always is reason for it be high often its a defence for some other problem. Read the literature before parroting industry hype re heart disease!
Posted by: Chris Gupta on August 17, 2004 05:37 PM
Serious musle pains and my liver enzimes have gone up five times to what they should be.Stomach pain gas and bloating have caused me serious problems.I am now looking for a natural cure.Coenzyme q10 i have now started 220mg.Help ideas
Posted by: Doug Lobo on August 17, 2004 07:43 PM
I have always had high levels of cholestrol, nevertheless, i did not change my diet at any time, i once took Zocor for 30 days and it was effective. Now my total Cholestrol is 302, and i was given Lipitor for 30 days. meanwhile i pursued this problem from a different angle by having Cupping Therapy done on my back and it is amazing how good i feel now, i have lots of energy and i only walk 30 minutes daily. my advice is to pursue cupping therapy, because it will significantly improve your health and raise your immunity, thus reducing your cholestrol and BP as well.
Mahmoud/ Egypt
Mahmoud1958@yahoo.com
Posted by: Mahmoud on September 8, 2004 10:52 AM
man, am i glad i found this site. been in lpitor for 3 days now. i was skeptical on taking it and this site has definitely made me think twice about continuuing its usage
Posted by: anthony on September 23, 2004 02:34 AM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Jamey on October 6, 2004 04:54 PM
I have beeb on lipitor for afew years now,and for the last three weeks have had horrendous pain in my ribs,and back.The doctor told me to stop the pill and see if the pain subsides,even a strong pain killer has not helped.iam hoping for agood result.
Posted by: WAYNE on October 26, 2004 06:25 PM
what stats are available re high cholestrol vs heart disease .all you hear is lower cholestrol but not why
Posted by: johan on October 31, 2004 03:54 AM
Both my parents had coronary difficulties and I have recenlty tesred with very high cholestrol levels. Five years ago they were 5.3, now 8.9. My physician,m who is also a homeopath is concerned enough to put me onto simvastatin to make an immediate impact on the levels. Thereafter, reducing and going onto a more natural route. I am 53 and never felt healthier. The side effects of simvastatin sound horrendous.
Posted by: vince on November 20, 2004 07:17 AM
I have develope joint pain which I believe is from taking Nician flush free
I take it in reading your report as best as I can understand it this can happen. Couyld I here more on this in laymen terms
Posted by: Leland on February 21, 2005 03:26 AM
I have high cholesterol and high liver enzymes after taking cholesterol medication.Does having high cholesterol cause you to have high liver enzymes?Are was it the medication that I was taking cause the liver enzymes to go up ? Thanks.Dinah Sudduth
Posted by: dinah sudduth on April 19, 2005 02:30 PM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: John Pitts on May 4, 2005 07:15 AM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Auggy Fitzgerald on October 26, 2005 04:10 AM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: john on May 30, 2007 12:11 PM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Frank on June 1, 2007 09:51 AM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: etele tamgbikison omietimi peters on June 22, 2007 06:17 PM
I have cholestrol & Triglyceride since 2003, i am regular taking phenolip-160 which is prescribed by my cardiologist. It was in conrtol due to medicine, change of food habit and regular walk/exercise. During my recent full body check up in a Hospital, I came to know it has incrased cholestrol from 200 to 237 & triglycerised from 175 to 285. I have consulted another DM Cardiologist and he has changed the medicine ( tonact TG & clopivasAP75 )which is very much helpful to me now and everthing is in control. Same medicine for years does not help in long run and some people like me require change of medicine
Posted by: Suresh Raichura on July 3, 2007 04:44 AM
why does no one realize that heart disease and cholesterol is not related its the BIGGEST myth of health. Someone needs to stop this myth
Posted by: chris on January 8, 2008 11:25 AM
I was on statins for 3 or 4 years. I complained of depression, fatigue, muscle aches, some memory loss, and weight gain. I was on 2 antidepressants, thyroid med, testosterone, and two blood pressure meds. Then I discovered Dr Gravelines' website. I have stopped both antidepressants, over time. Decreasing testosterone slowly, and started eating SATURATED fats. I now tell ever one I meet to STOP their Statins. This is a problem as I make my living as a pharmacist. At least I have no problem selling CQ10.
My I also suggest to everyone to look into the latest research on iodine. Check out Dr David Brownstein and his research www.optimox.com.
Posted by: Greg on February 13, 2008 04:06 PM
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