Statins May Cause Nerve Damage
"Researchers showed that people taking statins were 4 to 14 times more likely to develop polyneuropathy than those who did not take statins. Statins include Lescol, Lipitor, Mevacor, and Pravachol. Statins are highly effective in preventing heart attacks, so you should not stop taking them"
Here is a perfect example how the cholesterol myth has taken a life of its own. The lack of proof to support a link between cholesterol and heart disease does not deter the brainwashed proponents even when contrary evidence is starring them in the face. See:
Class Action - Statins Increases Heart Disease By 10% In Women
Chris Gupta
See also: Bad News About Statin Drugs
-------------------STATINS MAY CAUSE NERVE DAMAGE
Gabe Mirkin, M.D.
A Danish study reports that a small percentage of people who took statin drugs for several years to lower cholesterol developed a type of nerve damage called polyneuropathy.
Polyneuropathy is characterized by tingling, numbness and burning pain as well as decreased sensitivity to temperature or pain. When a person suffers nerve damage, a doctor is supposed to look for a cause, such as diabetes, lack of vitamin B12, Lyme disease, kidney disease, thyroid disease or alcohol abuse. People who had taken statins and developed polyneuropathies were checked for known causes of nerve damage. Researchers showed that people taking statins were 4 to 14 times more likely to develop polyneuropathy than those who did not take statins. Statins include Lescol, Lipitor, Mevacor, and Pravachol. Statins are highly effective in preventing heart attacks, so you should not stop taking them unless you develop aside effects such as polyneuropathy. Check with your doctor about any side effects from your medications.
Neurology May 14, 2002;58:1321-1322, 1333-1337
Abstract
Neurology 2002;58:1333-1337
© 2002 American Academy of NeurologyStatins and risk of polyneuropathy
A case-control study
D. Gaist, MD PhD, U. Jeppesen, MD PhD, M. Andersen, MD PhD, L. A. GarcÃa RodrÃguez, MD MSc, J. Hallas, MD PhD and S. H. Sindrup, MD PhD
From the Department of Neurology (Drs. Gaist, Jeppesen, and Sindrup), Odense University Hospital; Epidemiology (Dr. Gaist) and Clinical Pharmacology (Drs. Andersen, Hallas, and Sindrup), Institute of Public Health, University of Southern Denmark; and Centro Español de Investigación Farmacoepidemiológica (Dr. GarcÃa RodrÃguez), Madrid, Spain.
Address correspondence and reprint requests to Dr. David Gaist, Epidemiology, Institute of Public Health, University of Southern Denmark, Sdr Boulevard 23A, 5000 Odense C, Denmark; e-mail: dgaist@health.sdu.dk or dg@dadlnet.dk
Background: Several case reports and a single epidemiologic study indicate that use of statins occasionally may have a deleterious effect on the peripheral nervous system. The authors therefore performed a population-based study to estimate the relative risk of idiopathic polyneuropathy in users of statins.
Method: The authors used a population-based patient registry to identify first-time-ever cases of idiopathic polyneuropathy registered in the 5-year period 1994 to 1998. For each case, validated according to predefined criteria, 25 control subjects were randomly selected among subjects from the background population matched for age, sex, and calendar time. The authors used a prescription register to assess exposure to drugs and estimated the odds ratio of use of statins (ever and current use) in cases of idiopathic polyneuropathy compared with control subjects.
Results: The authors verified a diagnosis of idiopathic polyneuropathy in 166 cases. The cases were classified as definite (35), probable (54), or possible (77). The odds ratio linking idiopathic polyneuropathy with statin use was 3.7 (95% CI 1.8 to 7.6) for all cases and 14.2 (5.3 to 38.0) for definite cases. The corresponding odds ratios in current users were 4.6 (2.1 to 10.0) for all cases and 16.1 (5.7 to 45.4) for definite cases. For patients treated with statins for 2 or more years the odds ratio of definite idiopathic polyneuropathy was 26.4 (7.8 to 45.4).
Conclusions: Long-term exposure to statins may substantially increase the risk of polyneuropathy.
posted by Chris Gupta on Tuesday May 16 2006
URL of this article:
http://www.newmediaexplorer.org/chris/2006/05/16/statins_may_cause_nerve_damage.htm
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