Arthritis: Indomethacin Side Effects - Pumpkin Seed Oil Safer And More Effective

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Health through Nutrition

Practical Health

Yes this is very probable most of us eat too much sugar (carbs) and processed vegetable oils (which causes vitamin E deficiency as all is lost in processing). We are highly deficient in the Omega 3 and 9 fats and are literally phobic of good saturated fats. Pumpkin seeds are rich in the good fats which are absolutely essential to joint and health in general. Deficiency in these fats leads to all manner of problems such as heart disease, depression and cancer just to name a few... In addition to Pumpkin, flax seeds it is essential to include "Cod Liver Oil - Number One Superfood" in one's diet

See also:

Vitamin B3 and Arthritis

Boron and arthritis

How to Cheaply Obtain & Use Boron for Arthritis

While the following is on rats, nevertheless, it is prudent to note that the harmful side effects of the drug compared to the nutrient. Is it any wonder that they want to ban or control nutrients to protect their business with disease (pretentiously called Health)?

Chris Gupta
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Anti-Inflammatory Benefits in Arthritis

The healing properties of pumpkin seeds have also been recently investigated with respect to arthritis. In animal studies*, the addition of pumpkin seeds to the diet has compared favorably with use of the non-steroidal anti-inflammatory drug indomethacin in reducing inflammatory symptoms. Importantly, though, pumpkin seeds did not have one extremely unwanted effect of indomethacin: unlike the drug, pumpkin seeds do not increase the level of damaged fats (lipid peroxides) in the linings of the joints, a side-effect that actually contributes to the progression of arthritis.

*Effect of pumpkin-seed oil on the level of free radical scavengers induced during adjuvant-arthritis in rats.

Fahim AT, Abd-el Fattah AA, Agha AM, Gad MZ.

Biochemistry Department, Faculty of Pharmacy, Cairo University, Egypt.

Pumpkin-seed oil (PSO), a natural supplement rich with antioxidant ingredients, was given to rats in which arthritis was induced using Freund's complete adjuvant. Its effect was compared with that of indomethacin, as a classical anti-inflammatory agent. Two experimental patterns were studied, an acute phase that was applied only with PSO and a chronic phase applied for both PSO and indomethacin. Compared to normal untreated rats, it was shown that the induction of arthritis caused a decrease in serum sulphhydryl groups, with an increase in serum ceruloplasmin in both phases. Blood glutathione was first elevated in the acute phase, then its level was reduced in the chronic phase. Serum N-acetyl-beta-D-glucosaminidase activity was elevated only at the acute phase, while plasma total proteins and albumin were reduced at the chronic phase. Liver glucose-6-phosphate dehydrogenase activity was markedly increased, while no changes were observed in the levels of liver lipid peroxides and glutathione. These changes in the studied parameters were attributed to the superoxides and free radicals during arthritic inflammation. Administration of PSO succeeded in modulating most of the altered parameters affected during arthritis, especially at the chronic phase. Also, a remarkable inhibition of paw oedema was observed. A similar pattern was obtained upon treatment with indomethacin except that indomethacin markedly elevated liver lipid peroxides levels. Concurrent administration of PSO with indomethacin caused no changes in the parameters studied compared to that induced by treatment with indomethacin alone.

PMID: 7784309 [PubMed - indexed for MEDLINE]

Date: Mon, 11 Oct 2004 14:08:43 -0400
From: John McCullough
Subject: Home remedies.

Hi everyone,

Has anyone seen this before?

I found it in the letters to the editor in The Londoner, a local weekly paper which comes with the deluge of flyers.

God Bless and have a great Thanksgiving.

 

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posted by Chris Gupta on Thursday October 14 2004
updated on Saturday September 24 2005

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Readers' Comments

I want to know whether there is any real, proven treatment for cancer. Do fish oil and flax oil plus cottage cheese really help the patient? Will any natural/herbal natural unprocessed product help in osteo arthritis and diabetes? Kindly reply to my email also, as I do not get bandwidth to access all websites. Thanks.

Posted by: sharad c. kapadia on January 1, 2005 07:56 AM

 

hey just wanted to know if pumpkin seed oil can help overactive bladder

Posted by: melanie on January 25, 2005 11:41 PM

 

is there any limit on how much of pumpkin oil is enough daily?
thank you,
fred

Posted by: fred on February 2, 2006 09:00 AM

 

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