Health Supreme by Sepp Hasslberger

Networking For A Better Future - News and perspectives you may not find in the media

Networking For A Better Future - News and perspectives you may not find in the media

Health Supreme

News Blog

Site Map

NewsGrabs

Economy

Environment

Epidemics

Food for Thought

Health

Human Potential

Legislation

Pharma

Science

Society

Technology

The Media

War Crimes

 


Articles Archive

 

See also:

 

Communication Agents:

INACTIVE  Ivan Ingrilli
  Chris Gupta
  Tom Atlee
INACTIVE  Emma Holister
  Rinaldo Lampis
  Steve Bosserman
  CA Journal

 

Robin Good's
Web sites:

 

Activism:

 

AIDS:

 

Vaccines:

 

Pharma:

 

Information:

 

The Individual - Human Ability:

 

Society - Politics:

 

Economy:

 

Technology:

 

January 20, 2004

Vitamins E, C effective in high doses - prevent Alzheimers

While our legislative authorities are at great pains to protect us from the "potential" negative effects of supplementation of vital nutrients in high doses, there is a chance that they may have it all wrong.

The documented negative effects are those of approved and properly prescribed pharmaceutical drugs, which have become a major cause of death in western-medicine dominated areas.

Instead, more and more evidence is emerging for the absolutely vital nature of vitamins, and in much higher doses than those generally recommended, effective for the prevention of various diseases. Just yesterday I came across a connection of vitamin C deficiency to cot death or sudden infant death syndrome (SIDS), and here today a study which strongly suggests that the combination of vitamin C and E (in good high doses) will lower the risk of developing Alzheimer's disease:

Vitamin E, C Supplements May Prevent Alzheimer's

Mon January 19, 2004 05:09 PM ET
(Paper originally published in Archives of Neurology, news story by Reuters)

By Megan Rauscher

NEW YORK (Reuters Health) - A study involving more than 4700 participants strongly suggests that the combination of vitamin C and E lowers the risk of developing Alzheimer's disease.

As the lead investigator Dr. Peter P. Zandi told Reuters Health, properly conducted prevention trials are needed to confirm the results.

However, "because vitamins E and C are relatively non-toxic and are believed to have wide-ranging health benefits, they may offer a very attractive strategy for preventing Alzheimer's disease."

The findings come from the Cache County Study, which looked at the prevalence of Alzheimer's disease and other dementias in terms of genetic and environmental risk factors. As part of the study, people aged 65 and older were assessed for dementia between 1995 and 1997 and again between 1998 and 2000.

The participants were categorized as "vitamin E users" if they took an individual vitamin E tablet or a multivitamin containing more than 400 international units of vitamin E every day. They were classified as "vitamin C users" if they took at least 500 milligrams per day of vitamin C as a stand-alone tablet or in a multivitamin. If they took multivitamins containing lower doses of these two vitamins, they were categorized as "multivitamin users."

Zandi, at The Johns Hopkins University Bloomberg School of Public Health in Baltimore, and colleagues identified 200 cases of Alzheimer's disease between 1995 and 1997 and 104 new cases during follow-up of 4740 participants.

According to the team's analysis, reported in The Archives of Neurology, use of vitamin E and C supplements in combination lowered the odds of having Alzheimer's disease at the start of the study by about 78 percent, and the odds of developing the disease by about 64 percent during the follow-up period.

There was also a trend toward reduced Alzheimer's risk among people who took vitamin E and multivitamins containing vitamin C.

In contrast, there was "no evidence of a protective effect with the use of vitamin E or C supplements alone, with multivitamins alone, or with vitamin B-complex supplements."

Currently, the recommended daily allowance for vitamin E is 22 IU (15 mg) and for vitamin C, 75 to 90 mg, the team points out. Although multivitamin preparations typically contain approximately these levels, individual supplements commonly contain doses up to 1000 IU of vitamin E and 500 to 1000 mg or more of vitamin C.

"Our findings suggest that vitamins E and C may offer protection against AD when taken together in the higher doses available from individual supplements," the researchers conclude.

Zandi also pointed out that there may be a biological reason why the two vitamins together produce a benefit, related to the different duration of their antioxidant effects.

"Vitamin E is a lipid-soluble vitamin that sticks around in fat tissues of the body for a relatively long time," he explained. "In contrast, vitamin C is a water-soluble vitamin and is rapidly excreted from the body. Vitamin C may act to 'recharge' the antioxidant capacities of vitamin E so that the vitamin E can sustain its job of soaking up free radicals and relieving oxidative stress in the body."

SOURCE: Archives of Neurology, January 2004.


See also

Vitamin C may be a life-saver
Mega-doses of Vitamin C can counter avian flu, hepatitis and herpes, and can even control the advance of Aids - By Jane Feinmann
Imagine that a deadly virus is sweeping the world, killing and maiming hundreds of thousands of children. Nothing seems able to stop it - until a doctor stands up at the American Medical Association and reports on 60 cases involving severely infected children, all of whom have been cured. Yet his work, subsequently reported in a peer-review journal, is ignored, leaving the virus to wreak havoc for decades...

Vitamins 'cut Alzheimer's effect'

VITAMIN C AND CANCER: NEW DEVELOPMENTS

Discovery Shows New Vitamin C Health Benefits
Researchers in the Linus Pauling Institute at Oregon State University have made a major discovery about the way vitamin C functions in the human body - a breakthrough that may help explain its possible value in preventing cancer and heart disease.

The best and most complete treatment of Alzheimer's disease is Dr. Harold Foster's recent book "What really causes Alzheimer's disease". Foster describes and dissects the various factors we know play a role. He also examines currently available treatments and makes suggestions on how to prevent, that is, eliminate on a large scale, the factors that contribute to this illness.

The book is free and is available for download (or for purchase as a real dead-trees-and-ink book) from Harold Foster's website: www.hdfoster.com The link is "Publications".

Drugs Found Not to Work for Alzheimer's


And here a pertinent comment from Jon Rappoport


THOSE DAMN VITAMINS

JANUARY 21, 2004. The BBC reports on a new study probing the effects of vitamins on Alzheimer’s. Yes it is just a prelim study. Yes, other factors could be involved. And yes, since there is no established single root cause for Alzheimer’s, no one can define its parameters or say it is a single discrete condition.

BUT…I assure you, if researchers at, say, the US National Institutes of Health had found a DRUG with the effects of the vitamins, people there would be dancing in the aisles, breaking out the bubbly. There would be talk of med-science prizes.

AND there would be lots of heavy hitters in the Alzheimer’s field who would want that drug banned and destroyed, because the MONEY, the real money, is in treating Alzheimer’s, not preventing it.

Here is an excerpt from the BBC piece:

Lead researcher Dr Peter Zandi said: "These results are extremely exciting.

"Our study suggests that the regular use of vitamin E in nutritional supplement doses, especially in combination with vitamin C, may reduce the risk of developing Alzheimer's disease."

Dr Zandi's team examined data on 4,740 people aged 65 years or older. Of these 304 showed signs of Alzheimer's disease.

Approximately 17% of the study participants reported taking vitamin E or C supplements.

Another 20% used multivitamins, but without a high dosage of vitamin E or C.

Combination crucial

The researchers found that taking a combination of vitamin E and C seemed to have a protective effect.

People taking both vitamins were 78% less likely to show signs of Alzheimer's than those not taking the combination.

End of excerpt.

78% less likely to develop Alzheimer’s? That finding is fantastic. Now watch and see whether they really follow up with a large double-blind study, and if so, what results they say they obtain.

JON RAPPOPORT www.nomorefakenews.com


 


posted by Sepp Hasslberger on Tuesday January 20 2004
updated on Tuesday December 7 2010

URL of this article:
http://www.newmediaexplorer.org/sepp/2004/01/20/vitamins_e_c_effective_in_high_doses_prevent_alzheimers.htm

 


Related Articles

WHY YOU PROBABLY WON'T GET ALZHEIMER'S
Here is another reason why one must guard against the Medical Mafia or you will get the very disease that you think you are trying to protect. Need one say more on why the pharma cartel is afraid of nutrients. Chris Gupta ..."However, some specialists are beginning to realize that Alzheimer's is being overdiagnosed by at least 40 per cent. It's a convenient catch-all definition, much like ADHD in difficult... [read more]
September 13, 2003 - Chris Gupta

Estrogen Replacement And Alzheimer's
..."it bears repeating now — a 38% increased risk in anything as serious as dementia cannot be under-reported, in my opinion.".. Of course the immune enhancing, not toxic and. not to mention, low cost alternatives such as Vitamin C (see below) are just non issues. They will do anything for profits, at the expense of our health, while fooling us to think that they are doing it for our health....... [read more]
August 03, 2004 - Chris Gupta

Researchers: Vitamin C Deficiency Widespread - Link to Heart Disease, Infections, Cancer
In their book "Ascorbate - The Science of Vitamin C", Steve Hickey PhD and Hilary Roberts PhD point out that deficiency of vitamin C is far more widespread than is generally acknowledged by medical doctors and dieticians today. The two scientists, specialized in medical biophysics and nutrition, have challenged the scientific basis of the recommended daily amounts for this vitamin with medical authorities including the NIH - the National Institutes... [read more]
July 09, 2004 - Sepp Hasslberger

Bacteria Linked to Alzheimer's
Here's some indication that alzheimer's disease may have causation from Chlamydia pneumoniae bacteria. I figured sooner or later, they would find some type of bacterial or viral underpinning (or both). Hopefully these findings will incite additional research on this condition. Best wishes, Char Common Bacteria Linked To Alzheimer's Disease 3-22-4 (HealthDayNews) -- There's a link between the common respiratory bacteria Chlamydia pneumoniae and amyloid plaques found in the brains of... [read more]
March 24, 2004 - Chris Gupta

Tryptophan, Niacin Protect Against Alzheimer's
Niacin may protect against Alzheimer's disease, according to a recent study published in the Journal of Neurology, Neurosurgery, and Psychiatry, referenced in an article by Reuters News service. Susan commented on this as follows: Niacin works the same way as nicotine in that it protects the brain by stimulating the production of acetylcholine. The destruction of acetylcholine by such things as organophosphates, in fact, is the cause of BSE. Niacin... [read more]
July 16, 2004 - Sepp Hasslberger

The Negative Impact of Sugar on Vitamin C
Thanks Owen, exactly what I had suspected, one can also add alcohol to Dr. Ely's theory . The hit to the immune system by sugar is an added insult. See: Fibiger's Work on Cancer & Sugar Another good reason, from many, to ditch processed foods... Chris Gupta ----------------------- At 07:22 AM 7/22/2004, fonorow@internetwks.com wrote: FYI - Dr. John Ely has a Glucose Antagonism Theory - that since both glucose and... [read more]
August 04, 2004 - Chris Gupta

 

 

 


Readers' Comments


Vitamins E, C effective in high doses - prevent Alzheimers

What are they saying "high" is? They said that the combination is crucial and "high dose" is crucial but they don't explain the findings.



Posted by: Shelley Davis on January 22, 2004 04:56 PM

 


did you read the article?

I ask because it says in there:

The participants were categorized as "vitamin E users" if they took an individual vitamin E tablet or a multivitamin containing more than 400 international units of vitamin E every day. They were classified as "vitamin C users" if they took at least 500 milligrams per day of vitamin C as a stand-alone tablet or in a multivitamin. If they took multivitamins containing lower doses of these two vitamins, they were categorized as "multivitamin users."

it also says


Currently, the recommended daily allowance for vitamin E is 22 IU (15 mg) and for vitamin C, 75 to 90 mg, the team points out. Although multivitamin preparations typically contain approximately these levels, individual supplements commonly contain doses up to 1000 IU of vitamin E and 500 to 1000 mg or more of vitamin C.

"Our findings suggest that vitamins E and C may offer protection against AD when taken together in the higher doses available from individual supplements," the researchers conclude.

It seems that the best results were obtained when people took both C and E in the high doses range.

Posted by: Josef on January 27, 2004 02:28 PM

 


Here is a recent article that was published on Reuters, which I received with the following comment:

Niacin works the same way as nicotine in that it protects the brain by stimulating the production of acetylcholine. The destruction of acetylcholine by such things as organophosphates, in fact, is the cause of BSE.

Niacin May Protect Against Alzheimer's

By Anthony J. Brown, MD

NEW YORK (Reuters Health) - High intake of the vitamin niacin, particularly from food sources, may reduce the risk of Alzheimer's disease and age-related mental decline, according to a new report.

The study in the Journal of Neurology, Neurosurgery, and Psychiatry points out that severe niacin deficiency is known to cause dementia. However, the researchers note that it is unclear if more subtle variations in niacin intake influence the risk of mental deterioration.

"There have been no epidemiologic studies to look at the association between dietary niacin and Alzheimer's disease or cognitive decline," lead author Dr. Martha C. Morris, from the Rush Institute for Healthy Aging in Chicago, told Reuters Health.

Moreover, "animal studies and other studies have really focused on the effects of very high therapeutic dose levels of niacin," not amounts found in a standard diet.

To investigate, the researchers asked several thousand elderly people living in a Chicago community about the types and amounts of food they ate and tested their mental abilities.

The study focused on 815 randomly selected subjects who were free from Alzheimer's disease at the start of the study. After an average of nearly four years, 131 of the participants were diagnosed with Alzheimer's disease.

A high level of total niacin intake seemed to protect against both Alzheimer's disease and cognitive decline. The association was stronger for niacin intake from foods than for niacin taken in vitamin supplements.

"We were surprised to see a fairly strong association between niacin intake from foods and Alzheimer's disease," Morris said. Compared with the lowest intake, the highest intake "was linked to an 80 percent reduction in risk."

In the overall study population, high niacin intake was also linked to a reduced risk of cognitive decline.

Although the finding are provocative, Morris concluded, they will require verification before any changes to current dietary guidelines can be recommended.

SOURCE: the Journal of Neurology, Neurosurgery, and Psychiatry; August 2004. 

Posted by: Sepp on July 16, 2004 08:44 PM

 


Knowledge of Health, Inc.
457 West Allen Avenue #117 San Dimas, Ca. 91773 USA
Phone: 909 596-9507 Fax: 909 596-9189 Email: bsardi@aol.com

EXPERTS CALL FOR REVIEW OF RECOMMENDED DIETARY ALLOWANCE FOR VITAMIN C

With newly published research reports showing that higher concentrations of vitamin C can be achieved in the blood plasma than previously thought possible, antioxidant researchers have penned their names to a plea for a scientific re-evaluation of the Recommended Dietary Allowance (RDA) for vitamin C.

A dozen prominent antioxidant researchers, authors, and clinicians say the prevalent belief that 200 milligrams of oral vitamin C, an amount that can be obtained by eating five servings of selected fresh fruits and vegetables, can saturate the blood plasma and additional amounts are excreted in the urine, has now been disproved. Two recently published papers indicate that blood plasma levels of ascorbic acid can be raised three times greater than a flawed 1996 study indicates. One of the published studies shows that blood plasma concentrations of vitamin C continue to rise with a single 1000 milligrams dose of supplemental vitamin C.  

Drs. Steve Hickey and Hilary Roberts, pharmacology graduates of the University of Manchester in England assert the initial studies used to determine the blood plasma saturation point for vitamin C failed to calculate for the half life of this vitamin. In their newly published book, Drs. Hickey and Roberts show that the original calculations used to establish the RDA were performed 12 hours, or 24 half lives, after oral consumption of vitamin C and are therefore invalid. (Ascorbate: The Science of Vitamin C, 264 pages, referenced, ebook: www.lulu.com/ascorbate)

In addition to Drs. Hickey and Roberts, the list of researchers calling for a re-evaluation of the RDA for vitamin C includes: Thomas E. Levy MD, JD, author of Vitamin C, Infectious Diseases, and Toxins: Curing the Incurable (Philadelphia, PA: Xlibris Corporation; 2002); Robert F. Cathcart III, MD, a practicing physician and advocate of high oral-dose vitamin C therapy; Richard Passwater PhD, antioxidant researcher and author of Supernutrition; Patrick Holford, London, author of the Optimum Nutrition Bible; Dr Archie Kalokerinos, M.D., Graduate Sydney University, Australia, author of Vitamin C: Nature's Miraculous Healing Missile; Joel M. Kaufman, PhD, Professor of Chemistry Emeritus, University of the Sciences in Philadelphia, special interest in medicinal chemistry; Professor Ian Brighthope, Managing Director, Nutrition Care Pharmaceuticals Pty Ltd, Australia; Hugh D. Riordan, M.D., Director - Bio-Communications Research Institute, Wichita, Kansas; and Abram Hoffer, M.D., PhD., F.R.C.P., a practicing physician, advocate of nutritional medicine and editor of the Journal of Orthomolecular Medicine. 

The written plea was sent to the Institutes of Medicine, Food & Nutrition Board, which establishes the Recommended Dietary Allowances for essential nutrients. ####

A PLEA FOR SCIENTIFIC RE-EVALUATION OF THE RECOMMENDED DIETARY ALLOWANCE FOR VITAMIN C

August 23, 2004


Linda D. Meyers, PhD
Director, Food & Nutrition Board
Institute of Medicine
500 Fifth Street NW
Washington, DC 20001
Tel: 202.334.3153 Fax: 202.334.1412
Email: lmeyers@nas.edu

Catherine Woteki, PhD
Chair, Food & Nutrtion Board
Dean and Director
Department of Food Science and Human Nutrition
Iowa State Univ., College of Agriculture
138 Curtiss Hall
Ames, Iowa 50011
Phone: 515 294-2518  
Fax: 515 294-6800
Email agdean@iastate.edu

Paul M. Coates, PhD
Director
Office of Dietary Supplements
National Institutes of Health
Suite 3B01, MSC 7517
6100 Executive Boulevard
Bethesda, Maryland 20892-7517
Fax: 301 480-1845
Email: ds@nih.gov

Senator Thomas Harkin
Attention to: Peter Reinecke,
Chief of staff
731 Hart Senate Office Building
Washington, DC 20510
Phone: (202) 224-3254
Fax: (202) 224-9369
tom_harkin@harkin.senate.gov

PLEA CONCERNING ORAL VITAMIN C/RDA FOR VITAMIN C


As health professionals who have been involved in vitamin C research, it has recently come to our attention that higher blood plasma concentrations of vitamin C can be achieved through oral intake than previously thought possible. This scientific revelation has ramifications upon the current Recommended Dietary Allowance for vitamin C and personal health regimens for consumers. It is apparent the current published advice, that the blood plasma concentration for vitamin C is saturated at 200 milligrams oral consumption, must be revised. Furthermore, it is apparent the RDA for vitamin C needs immediate re-evaluation. We urge the scientific community and other responsible health authorities to take timely action to correct misinformation concerning oral dosing of vitamin C and to join an effort to re-evaluate the RDA for vitamin C.

Signed:

Steve Hickey Ph.D., Metropolitan University of Manchester, England. Co-author, Ascorbate, The Science of Vitamin C, www.lulu.com/ascorbate, 2004. ISBN 1-4116-0724-4 Telephone from USA: 011 44 161 962 5495

Hilary Roberts, Ph.D., graduate University of Manchester, England. Co-author, Ascorbate, The Science of Vitamin C, www.lulu.com/ascorbate, 2004. ISBN 1-4116-0724-4

Professor Ian Brighthope, Managing Director, Nutrition Care Pharmaceuticals Pty Ltd, 25 - 27 Keysborough Avenue, Keysborough Victoria 3173 Australia, Phone: +613 9769 0811, Fax: +613 9769 0822

Robert F. Cathcart III, M.D., advocate of high-dose vitamin C therapy; 127 Second Street, Suite 4, Los Altos, California 94022; Telephone: 650-949-2822; FAX: 650-949-5083

Abram Hoffer, M.D., PhD., F.R.C.P. ; Editor-in-chief of the Journal of Orthomolecular Medicine; Suite 3 - 2727 Quadra St ; Victoria, British Columbia V8T 4E5 Canada; Telephone: 250-386-8756; Fax 604-386-5828; email: hoffer@islandnet.com

Patrick Holford, London, founder of the Institute for Optimum Nutrition (ION) and the Brain Bio Centre; author of The Optimum Nutrition Bible, Tel: +44 (0)20 8871 2949 ex 22, Fax: +44 (0)20 8874 5003; Website: www.patrickholford.com

Dr Archie Kalokerinos, M.D., Graduate Sydney University. He is a Life Fellow of the Royal Society for Health, a Fellow of the International Academy of Preventive Medicine, Fellow of the Australasian College of Biomedical Scientists, and a Member of the New York Academy of Sciences. He has authored Vitamin C: Nature's Miraculous Healing Missile (1993). Currently he is semi-retired, living in Tamworth, New South Wales. Address: 20 Kennedy Close, Cooranbong, Australia, NSW 2265; Telephone: 61 2 4977 2957; Email: akalokerinos@optusnet.com.au

Joel M. Kauffman, PhD, Professor of Chemistry Emeritus, University of the Sciences in Philadelphia, Emeritus Professor of organic chemistry, MIT. Special interest in medicinal chemistry. 65 Meadowbrook Rd. Wayne, PA 19087-2510. Telephone: 215- 596-8839. Email: kauffman@hslc.org

Thomas Edward Levy, M.D., J.D., Tulane University School of Medicine, 1972-76-M.D.; Fellowship in Cardiology, 1979-81, Tulane Univ. Affiliated Hospitals; author, Vitamin C, Infectious Diseases, and Toxins: Curing the Incurable, Philadelphia, PA: Xlibris Corporation; 2002. Telephone: 800-331-2303, 719-548-1600; Fax 719 572-8081 or email to televymd@yahoo.com

Dr. Richard A. Passwater, Ph.D., antioxidant researcher, author "Supernutrition," Berlin, Maryland. Email: passwater@dmv.com Telephone: 410-641-7411.

Hugh D. Riordan, M.D., President - The Center for the Improvement of Human Functioning Int'l, Inc., Director - Bio-Communications Research Institute, 3100 North Hillside Avenue, Wichita, KS 67219 U.S.A., Phone: 316-682-3100, Fax: 316-682-5054, e-mail: bcri@brightspot.org, website: www.brightspot.org

Andrew W. Saul, PhD, Contributing Editor, Journal of Orthomolecular Medicine, Number 8 Van Buren Street, Holley, New York 14470 USA. Email: drsaul@doctoryourself.com


REFERENCES

Padayatty SJ, Sun H, Wang Y, Riordan HD, Hewitt SM, Katz A, Wesley RA, Levine M., Vitamin C pharmacokinetics: implications for oral and intravenous use, Annals Internal Medicine, April 6, 140: 533-37, 2004. National Institute of Diabetes and Digestive and Kidney Diseases, the National Cancer Institut, and the Clinical Center, National Institutes of Health, Bethesda, Maryland
20892-1372, USA.

BACKGROUND: Vitamin C at high concentrations is toxic to cancer cells in vitro. Early clinical studies of vitamin C in patients with terminal cancer suggested clinical benefit, but 2 double-blind, placebo-controlled trials showed none. However, these studies used different routes of administration.
OBJECTIVE: To determine whether plasma vitamin C concentrations vary substantially with the route of administration.
DESIGN: Dose concentration studies and pharmacokinetic modeling.
SETTING: Academic medical center.
PARTICIPANTS: 17 healthy hospitalized volunteers. MEASUREMENTS: Vitamin C plasma and urine concentrations were measured after administration of oral and intravenous doses at a dose range of 0.015 to 1.25 g, and plasma concentrations were calculated for a dose range of 1 to 100 g.
RESULTS: Peak plasma vitamin C concentrations were higher after administration of intravenous doses than after administration of oral doses (P smaller than 0.001), and the difference increased according to dose. Vitamin C at a dose of 1.25 g administered orally produced mean (+/-sd) peak plasma concentrations of 134.8 +/- 20.6 micromol/L compared with 885 +/- 201.2 micromol/L for intravenous administration. For the maximum tolerated oral dose of 3 g every 4 hours, pharmacokinetic modeling predicted peak plasma vitamin C concentrations of 220 micromol/L and 13 400 micromol/L for a 50-g intravenous dose. Peak predicted urine concentrations of vitamin C from intravenous administration were 140-fold higher than those from maximum oral doses.
LIMITATIONS: Patient data are not available to confirm pharmacokinetic modeling at high doses and in patients with cancer.
CONCLUSIONS: Oral vitamin C produces plasma concentrations that are tightly controlled. Only intravenous administration of vitamin C produces high plasma and urine concentrations that might have antitumor activity. Because efficacy of vitamin C treatment cannot be judged from clinical trials that use only oral dosing, the role of vitamin C in cancer treatment should be reevaluated.


Polidori MC, Mecocci P, Levine M, Frei B., Short-term and long-term vitamin C supplementation in humans dose-dependently increases the resistance of plasma to ex vivo lipid peroxidation, Archives Biochemistry Biophysics, March 423: 109-15, 2004. Institute of Biochemistry and Molecular Biology I, Heinrich-Heine University, Duesseldorf, Germany.

To assess the effects of short-term and long-term vitamin C supplementation in humans on plasma antioxidant status and resistance to oxidative stress, plasma was obtained from 20 individuals before and 2h after oral administration of 2g of vitamin C, or from eight subjects enrolled in a vitamin C depletion-repletion study using increasing daily doses of vitamin C from 30 to 2500 mg. Plasma concentrations of ascorbate, but not other physiological antioxidants, increased significantly after short-term supplementation, and increased progressively in the long-term study with increasing vitamin C doses of up to 1000 mg/day. Upon incubation of plasma with a free radical initiator, ascorbate concentrations were positively correlated with the lag phase preceding detectable lipid peroxidation. We conclude that vitamin C supplementation in humans dose-dependently increases plasma ascorbate concentrations and, thus, the resistance of plasma to lipid peroxidation ex vivo. Plasma and body saturation with vitamin C in humans appears desirable to maximize antioxidant protection and lower risk of oxidative damage.


Posted by: Sepp on August 25, 2004 06:01 PM

 















Security code:




Please enter the security code displayed on the above grid


Due to our anti-spamming policy the comments you are posting will show up online within few hours from the posting time.



 

   

The Individual Is Supreme And Finds Its Way Through Intuition

 

Creative Commons License
This work is licensed under a Creative Commons License.

These articles are brought to you strictly for educational and informational purposes. Be sure to consult your health practitioner of choice before utilizing any of the information to cure or mitigate disease. Any copyrighted material cited is used strictly in a non commercial way and in accordance with the "fair use" doctrine.

 

883



Enter your Email


Powered by FeedBlitz

 

 

Most Popular Articles
Lipitor: Side Effects And Natural Remedy

Lipitor - The Human Cost

Fluoride Accumulates in Pineal Gland

Original blueprints for 200 mpg carburetor found in England

Medical system is leading cause of death and injury in US

Aspartame and Multiple Sclerosis - Neurosurgeon's Warning

'Bird Flu', SARS - Biowarfare or a Pandemic of Propaganda?

 

 

More recent articles
Chromotherapy in Cancer

Inclined Bed Therapy: Tilt your bed for healthful sleep

European Food Safety Authority cherry picks evidence - finds Aspartame completely safe

Did Aspartame kill Cory Terry?

Retroviral particles in human immune defenses - is AIDS orthodoxy dead wrong?

Vaccine damage in Great Britain: The consequences of Dr Wakefield’s trials


Archive of all articles on this site

 

 

Most recent comments
Uganda: Pfizer Sponsored AIDS Institute Snubs Natural Treatment Options

Lipitor: Side Effects And Natural Remedy

AIDS: 'No Gold Standard' For HIV Testing

Lipitor: Side Effects And Natural Remedy

'Global Business Coalition' Wants More Testing: But Tests Do Not Show AIDS

 

 

Candida International

What Does MHRA Stand For??

Bono and Bush Party without Koch: AIDS Industry Makes a Mockery of Medical Science

Profit as Usual and to Hell with the Risks: Media Urge that Young Girls Receive Mandatory Cervical Cancer Vaccine

 

Share The Wealth

Artificial Water Fluoridation: Off To A Poor Start / Fluoride Injures The Newborn

Drinking Water Fluoridation is Genotoxic & Teratogenic

Democracy At Work? - PPM On Fluoride

"Evidence Be Damned...Patient Outcome Is Irrelevant" - From Helke

Why Remove Fluoride From Phosphate Rock To Make Fertilizer

 

Evolving Collective Intelligence

Let Us Please Frame Collective Intelligence As Big As It Is

Reflections on the evolution of choice and collective intelligence

Whole System Learning and Evolution -- and the New Journalism

Gathering storms of unwanted change

Protect Sources or Not? - More Complex than It Seems

 

Consensus

Islanda, quando il popolo sconfigge l'economia globale.

Il Giorno Fuori dal Tempo, Il significato energetico del 25 luglio

Rinaldo Lampis: L'uso Cosciente delle Energie

Attivazione nei Colli Euganei (PD) della Piramide di Luce

Contatti con gli Abitanti Invisibili della Natura

 

Diary of a Knowledge Broker

Giving It Away, Making Money

Greenhouses That Change the World

Cycles of Communication and Collaboration

What Is an "Integrated Solution"?

Thoughts about Value-Add

 

 

 

Best sellers from