Aspartame and Multiple Sclerosis - Neurosurgeon's Warning
Aspartame is a low calorie sweetener. Called a potent neurotoxin by several researchers, it is being sold as a sugar substitute for those on low calorie diets and for diabetics. If you like Coke or Pepsi "light", you certainly are at risk, but both industry and health officials deny that there is any truth to this story. Manufacturers have recently been sued in California.
Trade names for Aspartame are NutraSweet, Equal, Spoonful, Canderel, Benevia, Misura, but in Europe we often cannot recognize that Aspartame is part of what we're about to swallow unless we know that it also hides behind the seemingly innocuous "E 951" label. We might also watch out for warnings on food and drink labels that say: "contains a source of phenylalanine" or "phenylchetonurics should not consume this product".
In truth, no one should be consuming Aspartame and those responsible for putting it on the market - Donald Rumsfeld had a part in politically forcing its approval - should be held responsible for unleashing an agent of chemical warfare on an unsuspecting public.
Dr. Russell Blaylock, a recently retired neurosurgeon, has been warning for years and has even authored a book "Excitotoxins: The Taste That Kills". Blaylock says that Aspartame and Multiple Sclerosis are closely related. Unfortunately the Multiple Sclerosis society denies there is any connection between MS and Aspartame. The Society has chosen, according to Betty Martini, to hang on to industry funding rather than to warn its members. Blaylock explains the biological mechanism by which Aspartame circumvents the blood-brain-barrier and gets at the vital nervous tissues - the grey matter in our heads:
The Connection Between MS And Aspartame
By Russell L. Blaylock, MD
(originally published on Rense.com)
Recently, much controversy has surrounded a claim that aspartame may produce an MS-like syndrome. A current review of recent peer-reviewed scientific studies has disclosed a pathophysiological mechanism to explain this connection. As far back as 1996 it was shown that the lesions produced in the myelin sheath of axons in cases of multiple sclerosis were related to excitatory receptors on the primary cells involved called oligodendroglia. Recent studies have now confirmed what was suspected back then. The loss of myelin sheath on the nerve fibers characteristic of the disease is due to the death of these oligodendroglial cells at the site of the lesions (called plaques). Further, these studies have shown that the death of these important cells is as a result of excessive exposure to excitotoxins at the site of the lesions.
Normally, most of these excitotoxins are secreted from microglial immune cells in the central nervous system. This not only destroys these myelin-producing cells it also breaks down the blood-brain barrier (BBB), allowing excitotoxins in the blood stream to enter the site of damage. Aspartame contains the excitotoxin aspartate as 40% of its molecular structure. Numerous studies have shown that consuming aspartame can significantly elevate the excitotoxin level in the blood. There is a common situation during which the excitotoxin exposure is even greater. When aspartate (as aspartame) is combined in the diet with monosodium glutamate (MSG) blood levels are several fold higher than normal. With the BBB damaged, as in MS, these excitotoxins can freely enter the site of injury, greatly magnifying the damage. So, we see that dietary excitotoxins, such as aspartame and MSG, can greatly magnify the damage produced in multiple sclerosis. Likewise, excitotoxins have been shown to break down the BBB as well.
Of equal concern is observation that we know that about 10% of the population (based on autopsy studies of elderly) have MS lesions without ever developing the full blown disease, a condition called benign MS. A diet high in excitotoxins, such as aspartame, can convert this benign, subclinical condition into full-blown clinical MS. The amount of excitotoxins consumed in the average American diet is considerable, as shown by several studies. In addition, the toxin methanol is also in the aspartame molecule. Methanol is a axon poison. Combined toxicity of the aspartate and the methanol adds up to considerable brain toxicity and can convert benign, subclinical MS into full-blown MS. Once the MS becomes full-blown, further consumption of excitotoxins magnifies the toxicity, increasing disability and death.
Recent studies have also shown that even single exposures to these food-based excitotoxins can produce prolonged worsening of neurological lesions. In addition, it has been demonstrated that autoimmune reactions (as occur with MS) greatly magnify the toxicity of aspartate and glutamate (the excitotoxins). We also know liquid forms of excitotoxins are significantly more toxic because of rapid absorption and higher blood levels. In the face of this connection between excitotoxicity and the pathophysiology of MS, it would be ludicrous to allow further use of this excitotoxin containing sweetener.
1. Sannchez-Gomez MV, Malute C. AMPA and kainate receptors each mediate excitotoxicity in oligodendroglial cultures. Neurobiology of Disease 6:475-485, 1999
2. Yoshika A, et al. Pathophysiology of oligodendroglial excitotoxicity, J Neuroscience Research 46: 427-437, 1996.
3. Singh P, et al. Prolonged glutamate excitotoxicity: effects on mitochondrial antioxidants and antioxidant enzymes. Molecular Cell Biochemistry 243: 139-145, 2003.
4. Leuchtmann EA, et al. AMPA receptors are the major mediators of excitotoxin death in mature oligodendrocytes. Neurobiology of Disease 14:336-348, 2003.
5. Takahashi JL, et al. Interleukin1 beta promotes oligodendrocyte death through glutamate excitotoxicity. Annal Neurology 53: 588-595, 2003.
6. Pitt D, et al Glutamate uptake by oligodendrocytes: implications for excitotoxicity in multiple sclerosis. neurology 61: 1113-1120, 2003.
7. Soto A, et al. Excitotoxic insults to the optic nerve alter visual evoked potentials. Neuroscience 123: 441-449, 2004.
8. Blaylock RL. Interactions of cytokines, excitotoxins and reactive nitrogen and oxygen species in autism spectrum disorders. Journal of American Nutraceutical Association 6: 21-35, 2003.
9. Blaylock RL. Chronic microglial activation and excitotoxicity secondary to excessive immune stimulation: possible factors in Gulf War Syndrome and autism. Journal American Physicians and Surgeons, Summer, 2004.
TREATMENT FOR MS:
It is now known the cause for the destruction of the myelin in the lesions is overactivation of the microglia in the region of the myelin. An enzyme that converts glutamine to glutamate called glutaminase increases tremendously, thereby greatly increasing excitotoxicity. Mercury also activates microglia, even in subtoxic doses.
Any dietary excitotoxin can activate the microglia, thereby greatly aggravating the injury. This includes the aspartate in aspartame. The methanol adds to this toxicity as well. Now, the secret to treatment appears to be shutting down, or at least calming down, the microglia. It has been found that the antibiotic minocycline powerfully shuts down the microglia. I tried this treatment on a friend of mine who just came down with fulminant MS. He was confined to a wheelchair. I had him placed on minocycline and now, just a few weeks later, he is walking.
The good news is that other things also calm the microglia - the most potent are: silymarin, curcumin and ibuprophen. Phosphatidylcholine helps re-myelinate the nerve sheaths that are damaged, as does B12, B6, B1, vitamin D, folate, vitamin C, natural vitamin E (mixed tocopherols) and L-carnitine. DHA plays a major role in repairing the myelin sheath. Vitamin D may even prevent MS, but it acts as an immune modulator, preventing further damage - the dose is 2000 IU a day. Magnesium, as magnesium malate, is needed in a dose of 500 mg 2 x a day. They must avoid all excitotoxins, even natural ones in foods - such as soy, red meats, nuts, mushrooms and tomatoes. Avoid all fluoride and especially all vaccinations since these either inhibit antioxidant enzymes or triggers harmful immune reactions.
Dr. Blaylock is a recently retired board-certified neurosurgeon with more than twenty six years experience. He is a recently retired Clinical Assistant Professor of Neurosurgery at the Medical University of Mississippi. Author of thirty scientific papers on various medical subjects, chapters in three medical textbooks and a booklet on multiple sclerosis, he recently completed a booklet on bioterrorism and is the author of "Excitotoxins: The Taste That Kills", "Health & Nutrition Secrets to Save Your Life", and "Natural Strategies for Cancer Patients". (www.russellblaylockmd.com) He serves on the editorial staff of The Journal of American Physicians and Surgeons, the Journal of the American Nutraceutical Association, and acts as a medical advisor to the American Nutraceutical Association. His excellent newsletter can be gotten at his website. He lives in Ridgeland, Mississippi.
Note from Dr. Betty Martini :
Cori Brackett, co-owner of Sound and Fury Productions, an MS victim diagnosed at the Mayo Clinic, had a huge lesion in the brain. Cori was a user of the neurotoxic drug Aspartame, marketed as NutraSweet, Equal, Spoonful, E951, Canderel, Benevia, etc. Off the poison, she too walked out of her wheelchair; the lesion disappeared. Because of what she had endured from aspartame disease she felt a moral obligation to warn others, especially with 70% of the population and 40% of our children using this deadly toxin. Cori Brackett traveled 7000 miles and with 25 hours of footage produced the movie, "Sweet Misery: A Poisoned World." She says it reveals one of the most pervasive, insidious forms of corporate negligence in the history of the industrial revolution. On this date it is being released to the world. You will get to see the famed Dr. Blaylock and other aspartame experts, as well as hear the horror story of the victims. See Diane Fleming who is wilting in a Virginia prison because her athlete husband died of aspartame. She was sentenced to 50 years for the crime committed by the manufacturer who had the malice to market a poison. Don't miss this film. Contact Cori Brackett at Cori@soundandfuryproductions.com or (telephone) 520-624-9710. http://www.soundandfuryproductions.com
For years physicians have written the MS Society to alert them about aspartame. You can read my letter on http://www.dorway.com/nomarkle.html, never answered, of course. Faced with the choice of warning the public or continuing to receive funding from industry, the MS Society has chosen to sacrifice the victims. And when those responsible to solve the problem ARE the problem it is a sad commentary on greed and lack of concern for humanity. How can anyone set aside professional ethics to allow an MS holocaust, when simply alerting those with MS to avoid aspartame and other excitotoxins could save the lives of thousands. At one MS Society walk-a-thon, they were giving out free Diet Coke while trying to prevent our activists from giving walkers info that could save the lives of MS victims. I simply turned to the crowd and said: "The MS Society does not want you to have this life-saving information on a product triggering this disease." The entire crowd took copies. Later I received several calls of those who had heeded the advice and gotten well. But I shudder to think how many have perished because the MS Society hasn't had the integrity to warn victims.
Dr. Betty Martini, Founder
Mission Possible Intl.
9270 River Club Parkway
Duluth, Georgia 30097
WORLD NATURAL HEALTH ORGANIZATION
See more aspartame lawsuits filed against companies knowingly
poisoning the public on www.wnho.net
Aspartame Toxicity Center: www.holisticmed.com/aspartame
From the Orthomolecular Medicine News Service, October 4, 2006 - some more references to treatment options for MS. As always, don't take my word for it - if you have MS and want to do something about it, consult a medical doctor who is up-to-date on nutritional treatments.
VITAMINS FIGHT MULTIPLE SCLEROSIS
(OMNS) New research confirms that niacinamide, also known as vitamin B-3, is a key to the successful treatment of multiple sclerosis and other nerve diseases.  Niacinamide, say researchers at Harvard Medical School, "profoundly prevents the degeneration of demyelinated axons and improves the behavioral deficits."
This is very good news, but it is not at all new news. Over 60 years ago, Canadian physician H.T. Mount began treating multiple sclerosis patients with intravenous B-1 (thiamine) plus intramuscular liver extract, which provides other B-vitamins. He followed the progress of these patients for up to 27 years. The results were excellent and were described in a paper published in the Canadian Medical Association Journal in 1973. 
Mount was not alone. Forty years ago, Frederick Robert Klenner, M.D., of North Carolina, was using vitamins B-3 and B-1, along with the rest of the B-complex vitamins, vitamins C and E, and other nutrients including magnesium, calcium and zinc to arrest and reverse multiple sclerosis. [3,4] Klenner's complete treatment program was originally published as "Treating Multiple Sclerosis Nutritionally," Cancer Control Journal 2:3, p 16-20. His detailed megavitamin protocol is now posted for all interested persons to read at http://www.tldp.com/issue/11_00/klenner.htm
Drs. Mount and Klenner were persuaded by their clinical observations that multiple sclerosis, myasthenia gravis, and many other neurological disorders were primarily due to nerve cells being starved of nutrients. Each physician tested this theory by giving his patients large, orthomolecular quantities of nutrients. Mount's and Klenner's successful cures over decades of medical practice proved their theory was correct. B-complex vitamins, including thiamine as well as niacinamide, are absolutely vital for nerve cell health. Where pathology already exists, unusually large quantities of vitamins are needed to repair damaged nerve cells.
Nutritional therapy is inexpensive, effective and, most important, safe. There is not even one death per year from vitamins. 
Vitamin supplementation is not the problem. It is under-nutrition that is the problem. Vitamins are the solution.
Restoring health must be done nutritionally, not pharmacologically. All cells in all persons are made exclusively from what we drink and eat. Not one cell is made out of drugs.
 Kaneko S, Wang J, Kaneko M, Yiu G, Hurrell JM, Chitnis T, Khoury SJ, He Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J Neurosci. 2006 Sep 20;26(38):9794-804.
 Mount HT. Multiple sclerosis and other demyelinating diseases. Can Med Assoc J. 1973 Jun 2;108(11):1356-1358.
 Frederick R. Klenner. "Response of Peripheral and Central Nerve Pathology to Mega-Doses of the Vitamin B-Complex and Other Metabolites", Journal of Applied Nutrition, 1973,
 Dr. Klenner's "Clinical Guide to the Use of Vitamin C" (which discusses orthomolecular therapy with all vitamins, not just vitamin C) is now posted in its entirety. It includes a multiple sclerosis protocol, which takes up about five pages. See also: http://www.doctoryourself.com/klennerpaper.html
 Watson WA et al. 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2004 Sep;22(5):335-404.
Does aspartame multiply female MS?
At the American Academy of Neurology’s annual meeting, Dr. Gary Cutter, professor of Biostatistics at the University of Alabama, said women are now four times as likely as men to get multiple sclerosis: “It started at two-to-one and is now four-to-one.”
Aspartame, Anti-Depressants And Bush
By Jerry Mazza - Online Journal
Aspartame Warning (Video on YouTube)
Aspartame patent expired. We are now supposed to buy NEOTAME...
Date: Thu, 5 Aug 2004
Subject: [Health_and_Healing] Neotame---the 'exciting new sweetener'
The patent on Aspartame has run out---so our favorite health benefatctor--Monsanto has come up with a bigger better version...
Learn about this 'exciting new sweetener': http://www.neotame.com/
Learn MORE about this 'exciting new sweetener' http://www.holisticmed.com/neotame/
posted by Sepp Hasslberger on Thursday June 10 2004
updated on Saturday December 25 2010
URL of this article:
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