Glutathione Peroxidase - Selenium, Aminoacids Overcome AIDS
According to the Orthomolecular Medicine News Service"new clinical reports from Zambia, Uganda and South Africa indicate that AIDS may be stopped by nutritional supplementation. A number of members of the medical profession have observed that high doses of the trace element selenium, and of the amino acids cysteine, tryptophan, and glutamine can together rapidly reverse the symptoms of AIDS, as predicted by Dr. Harold D. Foster's nutritional hypothesis."
Yet, all the money for fighting AIDS is pumped into expensive and largely useless anti-retroviral drugs, which have been shown to cause the very symptoms that they are supposed to "treat".
Aids activists ask more drugs
Selenium is a mineral in the soil that gets taken up by plants grown for food use - and is an important anti-microbial nutrient. Areas that have low selenium concentrations in their soil are more likely to have high incidence of AIDS. It has been proposed in China to tackle both AIDS and the Bird Flu at the root by increasing the selenium content in food and animal feed.
Why can our health officials not look at this important breakthrough and try large scale supplementation? Certainly the cost would be ridiculous compared with the anti-retrovirals and the potential benefit - real prevention - would provide ample pay-back in no time.
Here is the recent piece from the Orthomolecular Medicine News Service...
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AIDS MAY BE A COMBINATION OF NUTRITIONAL DEFICIENCIES
HIV Depletes Body of Selenium and Three Amino Acids
(OMNS, April 26, 2006) New clinical reports from Zambia, Uganda and South Africa indicate that AIDS may be stopped by nutritional supplementation. A number of members of the medical profession have observed that high doses of the trace element selenium, and of the amino acids cysteine, tryptophan, and glutamine can together rapidly reverse the symptoms of AIDS, as predicted by Dr. Harold D. Foster's nutritional hypothesis. (1)
These nutrients are necessary for the human body to produce the enzyme glutathione peroxidase. This enzyme is strongly antiretroviral (it is an antagonist of reverse transcriptase) and can greatly reduce HIV replication. Unfortunately, HIV has developed the ability to compete with the body for these four nutrients because shortages of them allow its more effective replication. Specifically, HIV has a gene that allows it to produce an analogue of glutathione peroxidase.
Diets high in selenium, cysteine, tryptophan and glutamine seem to have two major benefits for AIDS patients:
1) They replace these four nutrients in the body, correcting the deficiencies HIV has caused. AIDS is what we call these combined deficiency symptoms.
2) High levels of these four key nutrients push up the body's glutathione peroxidase levels, making it much more difficult for HIV to replicate. This enzyme also beneficially interferes with the replication of Hepatitis B and C. Nutritionally treated patients are still HIV-positive, but seem to generally remain in good health unless they start to eat a diet that once again is poor in one or more of these nutrients. If this occurs, glutathione peroxidase levels fall, HIV begins to be replicated and the AIDS cycle begins again.
Some countries or regions, like Senegal and Bolivia, have been very fortunate. Their bedrock is naturally elevated in selenium and their diets are normally high in the three amino acids. As a result, they are rarely infected by HIV. Others, like Finland, have wisely mandated the addition of selenium to their fertilizers, with similar results. In contrast, some regions like Kwazulu Natal have bedrock and soils that contain little selenium and diets are poor in one or more of the key nutrients. For example, corn (maize) is low in both selenium and tryptophan. As a result, populations eating a great deal of corn are easy to infect with HIV and die very quickly of its associated nutritional deficiencies (AIDS).
To halt AIDS, to stop HIV from replicating, the needed nutrient levels are high. Selenium, for example, is taken at several times the commonly recommended daily allowance for the first month. Dosage is considered in more detail in "What Really Causes AIDS." (2) This book is available for free reading and downloading at www.hdfoster.com .
What is Orthomolecular Medicine?
Linus Pauling defined orthomolecular medicine as "the treatment of disease by the provision of the optimum molecular environment, especially the optimum concentrations of substances normally present in the human body." Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org
The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource.
Editorial Review Board:
Abram Hoffer, M.D., Ph.D.
Harold D. Foster, Ph.D.
Bradford Weeks, M.D.
Carolyn Dean, M.D. N.D.
Erik Paterson, M.D.
Thomas Levy, M.D., J.D.
Steve Hickey, Ph.D.
Andrew W. Saul, Ph.D., Editor. Email: firstname.lastname@example.org
1. Foster HD. How HIV-1 causes AIDS: Implications for prevention and treatment," Medical Hypotheses, Vol. 62(4), p 549-553, 2004.
2. Foster HD. What really causes AIDS. Victoria, BC: Trafford, 2002. Free download at www.hdfoster.com .
For further reading:
"HIV/AIDS: a nutrient deficiency disease," Journal of Orthomolecular Medicine, 2005, Vol. 20(2), p 67-69.
Environmental factors and the pathogenesis of selenium-CD-4 cell tailspin in AIDS. Chinese Journal of AIDS and STD, Vol. 10(5), p 390-392,402 2004.
AIDS and the selenium-CD4T cell tailspin," World Journal of Infection, Vol. 3(6), p 456-459, 2003.
Micronutrients in pathogenesis and treatment of AIDS," Foreign Medical Sciences: Section of Medgeography, Vol. 24(2), p 49-53, 2003.
Why HIV-1 has diffused so much more rapidly in Sub-Saharan Africa than in North America. Medical Hypotheses, Vol. 60(4), p 611-614, 2003.
"How HIV-1 kills: Implications for the treatment and prevention of AIDS. Townsend Letter for Doctors and Patients, No. 255, p 76-78, 2002.
"Aids and the 'selenium - CD4T cell tailspin': the geography of a pandemic," Townsend Letter for Doctors and Patients, No. 209, p 94-99, 2000.
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Cal Crilly has some more data on aids and selenium:
Hello to you all,
This may be of interest and is a very cheap and non toxic way to address AIDS.
I believe the Selenium effects HIV via two mechanisms. Higher Selenium levels will create Glutathione, this is cell protective and simply reduces T-cell turn over by protecting cells from antioxidant damage.
The other is because of Methylation. HIV and all our own retroviruses are suppressed by Methylation and this is done with a Selenium compound called S-Adenosylmethionine or SAMe.
If Selenium levels drop both Glutathione and SAMe are reduced causing cell damage and hypomethylation of the genome. This causes HIV levels to rise. AIDS drugs such as AZT cause hypermethylation of the genome and inhibit HIV but are toxic. SAMe is cheaper, more effective and non toxic in the doses required. Links to relevant articles are below.
"NEW YORK (Reuters Health) - Selenium supplements can slow the rise in virus levels in HIV-positive patients, which allows the number of beneficial CD4 immune cell to increase, according to results of a clinical trial supported by grants from the National Institutes of Health.
Low blood levels of selenium have been linked to high HIV virulence and more opportunistic infections, Dr. Barry E. Hurwitz and associates at the University of Miami in Florida report in the Archives of Internal Medicine. In lab experiments, the element suppresses HIV-1 replication.Â”
SOURCE: Archives of Internal Medicine, January 22, 2007.
Selenium may help lower HIV levels
"The methylation and transsulfuration pathways are intimately linked and have been implicated in the progression of neurologic damage and immune cell depletion caused by human immunodeficiency virus (HIV) infection. We studied the following metabolites related to these pathways: S-adenosylmethionine (SAMe), homocysteine, cysteine, cysteinyl-glycine, and glutathione (GSH) in blood and CSF of 16 HIV-infected patients with neurologic complications and 20 HIV-negative control patients undergoing lumbar punctures for other medical reasons. We confirmed recent studies of decreased CSF SAMe concentrations in HIV infection and demonstrated that diastereomers of SAMe are present in CSF but not in plasma or erythrocytes from both HIV-infected and HIV-negative patients. In HIV-infected patients, CSF GSH and cysteinyl-glycine, but not homocysteine or cysteine, were significantly reduced. This is the first report of decreased CSF GSH induced by HIV infection. GSH has a regulatory effect on the synthesis of SAMe in hepatic tissue, and the same mechanism may also apply in the CNS. Administration of SAMe-butanedisulphonate, 800 mg/d intravenously for 14 days, was associated with significant increases in CSF SAMe and GSH. These findings have potentially important therapeutic implications for the use of SAMe in protecting against SAMe and GSH deficiency in the CNS of HIV-infected patients.Â”
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Harold Foster is doing trials in Africa with Selenium and it would be good to observe his work.
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"Intracellular levels of glutathione are depleted in patients with acquired immunodeficiency syndrome in whom the risk of tuberculosis, particularly disseminated disease is many times that of healthy individuals. In this study, we examined the role of glutathione in immunity against tuberculosis infection in samples derived from healthy and human immunodeficiency virus infected subjects. Our studies confirm that glutathione levels are reduced in peripheral blood mononuclear cells and in red blood cells isolated from human immunodeficiency virus-infected subjects (CD4>400/cumm). Furthermore, treatment of blood cultures from human immunodeficiency virus infected subjects with N-acetyl cysteine, a glutathione precursor, caused improved control of intracellular M. tuberculosis infection."
New trading patterns blamed for selenium intake decline
... average intake of selenium in the UK has fallen from 60 to 34 micrograms per day. The European recommended daily intake (RDI) is 65 micrograms ... geographical studies ... have shown a consistent trend for populations with low selenium intakes to have higher cancer mortality rates. And a study carried out in France ... which followed a group of 1,389 elderly volunteers to for a period of nine years, found that those with low selenium diets were considerably more likely to die from cancer than those with high selenium diets.
Selenium supplements may contribute to reduced HIV viral load
"The intervention resulted in no adverse events related to the study supplement," the authors write. The two groups had similar selenium levels at the beginning of the study, but after nine months of treatment, the average change in blood selenium level was greater in the treatment group. Higher blood selenium levels predicted a decreased HIV viral load, which in turn predicted increased CD4 count.
"The exact mechanism by which selenium exerts its effects on HIV-1 viral replication is not known, although the literature suggests several possibilities," the authors write. One hypothesis holds that selenium's antioxidant properties may repair damage done to immune cells by oxygen, which is produced at higher levels in the bodies of patients with HIV. However, future research is needed to confirm this relationship.
Selenium pills 'may combat HIV'
The University of Miami found a lower HIV viral load in patients who took selenium supplements for nine months. Selenium deficiencies have been recorded in HIV patients, and evidence suggests the mineral can improve the function of the immune system.
Selenium for AIDS - CBC Interview
(taken off YouTube)
CBC interview with Norman Sartor, HIV positive, who takes Selenium and amino acid supplements in accordance with discoveries by Dr Harold Foster, author of "What really causes Aids", a freely downloadable book.
posted by Sepp Hasslberger on Wednesday April 26 2006
updated on Tuesday December 21 2010
URL of this article:
Selenium Status Is Associated With Accelerated HIV / AIDS
Thanks for sending me this note Harry, then again ethics is not a strong factor amongst the medical Mafiosi - particularly when, egos, greed and wealth have superceded their consciousness. Concern for health, their supposedly original good intentions, have turned to pretense, and have simply become a tool to accomplish their goals incognito... Even more abominable is the zeal with which toxic drugs and immunization are thrust on the sick... [read more]
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The officially supported theory of AIDS as an illness caused by a continually mutating retrovirus called HIV has not led to progress in controlling the epidemic in over two decades. We are still looking for a vaccine but chances are it will never be found. We are still treating those reacting positively to a non-virus-specific test with toxic medications, but the results are less than brilliant. The existence of long-term... [read more]
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As reported today in the Boston Globe, a research program undertaken by Wafaie Fawzi, Associate Professor of Nutrition and Epidemiology at the Harvard School of Public Health, has found that a multivitamin supplement containing vitamins of the B Complex with C and E was effective in slowing the progression from 'HIV infection' to the clinical picture of AIDS. The study is published in the New England Journal of Medicine and... [read more]
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Nevirapine has been in the news recently over a study in Africa, where researchers apparently "forgot" to report numerous serious side effects and even several deaths. The study was to prove efficacy in reducing HIV transmission from pregnant mothers to their newborns, but researchers also "forgot" to include a control group of mothers that did not receive the drug. Grave oversights? Apparently the US health authorities thought so, because the... [read more]
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